Transcriptomics

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Effect of prenatal exposure to nicotine on kidney structure and gene expression in rats


ABSTRACT: Here, we investigated whether prenatal exposure to nicotine alters kidney glomerular mass and genome-wide gene expression profiles in two genetically distant strains of rats, namely spontaneously hypertensive rats (SHR) and Brown Norway (BN) rats. Nicotine or saline were administered to BN and SHR dams via osmotic pumps throughout gestation. Kidneys from 9-week-old male offspring were studied.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE29677 | GEO | 2012/12/25

SECONDARY ACCESSION(S): PRJNA141197

REPOSITORIES: GEO

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