Transcriptomics

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Systems analysis identifies an essential role for SHARPIN in macrophage TLR2 responses (Affymetrix)


ABSTRACT: Our systems analysis reported here demonstrates that TLR-responses in macrophages are markedly impaired by SHARPIN deficiency, and that SHARPIN controls expression of a subset of TLR2-induced, NF-kB and AP-1 dependent genes that overlaps with those affected by the hypomorphic panr2 mutation in NEMO.

ORGANISM(S): Mus musculus

PROVIDER: GSE29891 | GEO | 2011/08/31

SECONDARY ACCESSION(S): PRJNA155335

REPOSITORIES: GEO

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