Transcriptomics

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Continued studies the glycosylation changes in a cell line model of embryo implantation of steroid-exposed and control Ichikawa cells


ABSTRACT: This experiment continues our investigation of glycosylation in endometrial epithelium. During the menstrual cycle, estrogen and progesterone sensitise the uterus to the implanting embryo. There is a major expansion of Golgi and secretory function with increases in mucin (MUC1) and the appearance of specific glycans. We are using Ishikawa cells as a model for in vitro implantation, and have shown the presence of steroid receptors and alterations in glycosylation after hormone exposure.

ORGANISM(S): Homo sapiens

PROVIDER: GSE29940 | GEO | 2011/06/14

SECONDARY ACCESSION(S): PRJNA140773

REPOSITORIES: GEO

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