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Silencing of HAI-1 in a human oral squamous cell carcinoma cell line, SAS

ABSTRACT: To examine the role of hepatpcyte growth factor activator inhibitor type 1 (HAI-1) in cancer, we analyzed effect of HAI-1 silencing on gene expression profiles of human oral squamous cell carcinoma cell line, SAS. We used short hairpin RNA (shRNA) directed against HAI-1 mRNA. We constructed retroviral vectors which showed stable and significant silencing effects on HAI-1 genes of SAS. Microarray data of the expression profiles of duplicated experiments of HAI-1-knockdown SAS with that from the control cell are shown.

ORGANISM(S): Homo sapiens

PROVIDER: GSE32142 | GEO | 2012/01/25

SECONDARY ACCESSION(S): PRJNA147659

REPOSITORIES: GEO

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