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Expression data from human iPS cells treated by a small molecule KY02111

ABSTRACT: Human pluripotent stem cells (hPSCs) such as embryonic stem cells and induced pluripotent stem cells are promising materials for cell-based regenerative therapies to heart diseases. However, until realization there are many hurdles such as high efficiency of cardiac differentiation of hPSCs and production of clinical-grade cardiac cells derived from hPSCs. Here, we show that a novel small molecule KY02111 robustly enhances differentiation to functional cardiomyocytes from hPSCs. To reveal how KY02111 function on promoting cardiac differentiation of hPSCs, we analyzed the gene expression profiles in KY02111-treated IMR90-1 hiPSCs using the microarray technique.

ORGANISM(S): Homo sapiens

PROVIDER: GSE33622 | GEO | 2012/10/30

SECONDARY ACCESSION(S): PRJNA148503

REPOSITORIES: GEO

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Expression data from human iPS cells treated by a small molecule KY02111

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