Transcriptomics

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Comparison of gene expression alterations induced by distinct PI3K inhibitors


ABSTRACT: The goal is the characterization of the off-target activity of BKM120 observed in A2058 human melanoma cell line at IC90 concentration (3.606 µM) but not at lower concentrations. Controls are BEZ235, GDC0941, showing no off-target activity. A secondary objective is the characterizations of drug effects on transcript expression with respect to a control treatment (DMSO) of those PI3K inhibitors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE33643 | GEO | 2012/07/01

SECONDARY ACCESSION(S): PRJNA148663

REPOSITORIES: GEO

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