Transcriptomics

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Role and function of SPRY1/2 in BCR-ABL1 driven pre-B cells

ABSTRACT: In order to investigate the function of SPRY1 and SPRY2 in ALL, we isolated bone marrow cells from Spry1 and 2 fl/fl mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven pre-B cells were transformed either with CRE-ERT2 or ERT2 (PMIP) and after 2 days of treatment with 4OH-Tamoxifen (0.5 micromolar) subjected to gene expression analysis.

ORGANISM(S): Mus musculus

PROVIDER: GSE34834 | GEO | 2013/06/03

SECONDARY ACCESSION(S): PRJNA150225

REPOSITORIES: GEO

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