Genomics

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Formaldehyde and Epigenetic Alterations: MicroRNA Changes in the Nasal Epithelium of Nonhuman Primates


ABSTRACT: We set out to test the hypothesis that formaldehyde inhalation exposure significantly alters miRNA expression profiles within the nasal epithelium of nonhuman primates. Here, cynomolgus macaques were exposed to 0, 2, and 6 ppm formaldehyde for 6 hours/day across two consecutive days. RNA was extracted from the nasal maxilloturbinate region, a direct target of formaldehyde inhalation exposure. Genome-wide miRNA expression levels were assessed using microarrays.

ORGANISM(S): Homo sapiens Macaca fascicularis

PROVIDER: GSE34978 | GEO | 2012/09/01

SECONDARY ACCESSION(S): PRJNA151111

REPOSITORIES: GEO

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