Methylation profiling

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Methylated CpG island amplification (MCA) microarray analysis of human colorectal tumors


ABSTRACT: The concept of the CpG island methylator phenotype (CIMP) in colorectal cancer (CRC) is widely accepted, though the timing of its occurrence and its interaction with other genetic defects are not fully understood. Our aim in this study was to unravel the molecular development of CIMP cancers by dissecting their genetic and epigenetic signatures in precancerous and malignant colorectal lesions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE35508 | GEO | 2012/08/31

SECONDARY ACCESSION(S): PRJNA156105

REPOSITORIES: GEO

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