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Evaluation of Human Embryonic Stem Cells and their 1 Differentiated Fibroblastic Progenies as Cellular Models for In Vitro Genotoxicity Screening

ABSTRACT: This study evaluated human embryonic stem cells (hESC) and their differentiated fibroblastic progenies as cellular models for genotoxicity screening. The DNA damage response of hESCs and their differentiated fibroblastic progenies were compared to a fibroblastic cell line (HEPM, CRL1486) and primary cultures of peripheralblood lymphocytes (PBL), upon exposure to gamma irradiation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE36355 | GEO | 2014/07/30

SECONDARY ACCESSION(S): PRJNA153319

REPOSITORIES: GEO

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