Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Tiling ChIP-CHIP Ssn6-GFP, Tp11-GFP, Tup12-GFP; Hst4 vs WT Expression

ABSTRACT: Tiling ChIP-CHIP Ssn6-GFP, Tp11-GFP, Tup12-GFP and Hst4 vs WT Expression

ORGANISM(S): Schizosaccharomyces pombe

PROVIDER: GSE36429 | GEO | 2012/03/13

SECONDARY ACCESSION(S): PRJNA153235

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Tiling ChIP-CHIP Ssn6-GFP, Tp11-GFP, Tup12-GFP; Hst4 vs WT Expression

Project description:Tiling ChIP-CHIP Ssn6-GFP, Tp11-GFP, Tup12-GFP and Hst4 vs WT Expression 6 Samples

2012-03-13 | E-GEOD-36429 | biostudies-arrayexpress

Schizosaccharomyces pombe

Project description:Tiling ChIP-CHIP Ssn6-GFP, Tp11-GFP, Tup12-GFP Hst4 vs WT Expression

| PRJNA153235 | ENA

Ssn6-GFP ChIP-CHIP

Project description:We have performed a genome wide investigation for the binding locations of the transcriptional co-repressor proteins Ssn6, Tup11 and Tup12 in the fission yeast Schizosaccharomyces pombe. We have used a ChIP protocol described previously (Robyr et al, 2003) with microarrays containing ORF and IGR fragments representing the complete fission yeast genome (Wiren et al, 2005). Keywords: ChIP-CHIP

2006-11-15 | GSE4503 | GEO

The fission yeast Schizosaccharomyces pombe: H3K9me2 and Fep1-GFP ChIP-chip

Project description:ChIP-chip analyses of H3K9me2 (in WT 30°C, WT 18°C, ccr4∆ 18°C, ccr4∆fep1 18°C, ago1∆ 18°C, WT + 2,2′-bipyridyl 18°C), Fep1-GFP (in WT), Ssn6-MYC ChIP in WT and Fep1∆.

2018-05-08 | GSE104528 | GEO

Ssn6 Overexpression

Project description:We have performed a genome wide expression profile study of the essential transcriptional co-repressor protein Ssn6 in Schizosaccharomyces pombe. Ssn6 affected targets were identified by over expression of Ssn6 protein in a WT strain. A WT strain holding a plasmid expressing Ssn6 (pDUAL-Ssn6) was compared against the expression in a WT with the empty plasmid (pDUAL-EMPTY) strain. Keywords: Overexpression/WT

2006-11-15 | GSE4502 | GEO

Schizosaccharomyces pombe

Project description:Ssn6-GFP ChIP-CHIP

| PRJNA104681 | ENA

GFP ChIP-seq in Smchd1-GFP NSCs

Project description:GFP ChIP-seq in Smchd1-GFP NSCs

| PRJNA728088 | ENA

Tup12-GFP ChIP-CHIP

2006-11-15 | GSE4506 | GEO

Tup11-GFP ChIP-CHIP

2006-11-15 | GSE4505 | GEO

Global Regulation of Nucleosome Organization And Transcription By The Yeast Ssn6-Tup1 Corepressor (expression)

Project description:The yeast Ssn6-Tup1 complex regulates gene expression through a variety of mechanisms, including positioning of nucleosomes over promoters of some target genes to limit accessibility to the transcription machinery. To further define the functions of Ssn6-Tup1 in gene regulation and chromatin remodeling, we performed genome-wide profiling of changes in nucleosome organization and gene expression that occur upon loss of SSN6 or TUP1, and observed extensive nucleosome alterations in both promoters and gene bodies of derepressed genes. Our improved nucleosome profiling and analysis approaches revealed low-occupancy promoter nucleosomes (P nucleosomes) at locations previously defined as nucleosome-free regions. In the absence of SSN6 or TUP1, this P nucleosome is frequently lost, whereas nucleosomes are gained at -1 and +1 positions, accompanying up-regulation of downstream genes. Our analysis of public ChIP-seq data revealed that Ssn6 and Tup1 preferentially bind TATA-containing promoters, which are also enriched in genes derepressed upon loss of SSN6 or TUP1. These results suggest that stabilization of the P nucleosome on TATA-containing promoters may be a central feature of the repressive chromatin architecture created by the Ssn6-Tup1 corepressor, and that releasing the P nucleosome contributes to gene activation.

2012-10-10 | GSE37466 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data