Transcriptomics

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Expression Data from HNF1b-knockdown RMG2-ovarian cancer cells


ABSTRACT: Ovarian clear cell carcinoma (OCCC) is a morphologically and biologically distinct subtype of ovarian carcinomas. We previously reported a gene expression profile characteristic of OCCC (OCCC signature), which contains hepatocyte nuclear facter-1b ( HNF-1b). To elucidate the biological role of HNF-1b in OCCC, we performed the suppression of the HNF-1b expression in human ovarian cancer cell line RMG2 using short hairpin RNA. We are now evaluating the functional effect using these cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE37290 | GEO | 2012/05/01

SECONDARY ACCESSION(S): PRJNA159411

REPOSITORIES: GEO

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