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Gene expression profiling of ovaries collected from mice treated with or without Ulipristal

ABSTRACT: Ulipristal acetate (UPA), also referred to as VA/CDB-2914, is a new and promising emergency contraceptive. It is a selective progesterone receptor modulator (SPRM) that has been approved in Europe and the USA for emergency contraception.

ORGANISM(S): Mus musculus

PROVIDER: GSE37353 | GEO | 2012/10/04

SECONDARY ACCESSION(S): PRJNA159813

REPOSITORIES: GEO

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Gene expression profiling of ovaries collected from mice treated with or without Ulipristal

Project description:Ulipristal acetate (UPA), also referred to as VA/CDB-2914, is a new and promising emergency contraceptive. It is a selective progesterone receptor modulator (SPRM) that has been approved in Europe and the USA for emergency contraception. To experimentally induce ovulation, the immature CD-1 mice (24–28 d old) were injected ip with 5 IU of PMSG and 48 h later by 5 IU of hCG. Two hour after hCG treatment, mice were administered with UPA/CDB or vehicle/OIL. Ovaries were collected at 11 h and total RNA was analyzed using Affymetrix mouse arrays

2012-10-04 | E-GEOD-37353 | biostudies-arrayexpress

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Effects of Injectable DMPA and Combined Oral Contraceptive Use on HIV Susceptibility Factors in Pig-tailed Macaques

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Genes linked to cervicovaginal integrity are dysregulated in DMPA but not COC contraception users

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