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Murine forestomach epithelial sheets: Controls vs. Sox2 overexpression mutants

ABSTRACT: Transcriptional profiling of adult forestomach epithelium comparing K5-CreER controsl with K5-CreER;Rosa26Sox2/Sox2 mutants. Two doses of tamoxifen were given and four weeks later the epithelal sheets were harvested for RNA extraction. Goal was to determine the effects of Sox2 overexpression on epithelial phenotypic changes.

ORGANISM(S): Mus musculus

PROVIDER: GSE37857 | GEO | 2012/05/09

SECONDARY ACCESSION(S): PRJNA164691

REPOSITORIES: GEO

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Murine forestomach epithelial sheets: Controls vs. Sox2 overexpression mutants

Project description:Transcriptional profiling of adult forestomach epithelium comparing K5-CreER controsl with K5-CreER;Rosa26Sox2/Sox2 mutants. Two doses of tamoxifen were given and four weeks later the epithelal sheets were harvested for RNA extraction. Goal was to determine the effects of Sox2 overexpression on epithelial phenotypic changes. Two-condition experiment, wildtype Vs Sox2 overexpression mutant. Biological replicates: 3 control replicates, 3 mutant replicates.

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