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Microarray analysis on brains of mice fed a normal diet and supplemented with either oil palm phenolics (OPP) or distilled water

ABSTRACT: OPP (1500 ppm gallic acid equivalent (GAE)) was supplemented to BALB/c mice given a normal diet to observe for possible neuroprotective effects. Brains were harvested six weeks after the feeding regimen for gene expression studies. Results from the separate microarray data analysis carried out on the different organs show that OPP have neuroprotective properties in vivo.

ORGANISM(S): Mus musculus

PROVIDER: GSE40030 | GEO | 2012/08/12

SECONDARY ACCESSION(S): PRJNA172420

REPOSITORIES: GEO

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Microarray analysis on brains of mice fed a normal diet and supplemented with either oil palm phenolics (OPP) or distilled water

Project description:OPP (1500 ppm gallic acid equivalent (GAE)) was supplemented to BALB/c mice given a normal diet to observe for possible neuroprotective effects. Brains were harvested six weeks after the feeding regimen for gene expression studies. Results from the separate microarray data analysis carried out on the different organs show that OPP have neuroprotective properties in vivo. Total RNA obtained from brains of BALB/c mice given OPP (six weeks after the feeding regimen) were compared to controls given distilled water (three replicates in the treatment group versus three replicates in the control group)

2012-08-11 | E-GEOD-40030 | biostudies-arrayexpress

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Microarray analysis on livers, spleens and hearts of mice fed a normal diet and supplemented with either oil palm phenolics (OPP) or distilled water

Project description:OPP (1500 ppm gallic acid equivalent (GAE)) was supplemented to BALB/c mice given a normal diet to observe for possible biological activities. Livers, spleens and hearts were harvested six weeks after the feeding regimen for gene expression studies. Results from the separate microarray data analysis carried out on the different organs show that OPP may have pleiotropic biological properties in vivo. Total RNA obtained from livers, spleens and hearts of BALB/c mice given OPP (six weeks after the feeding regimen) were compared to controls given distilled water (liver: three replicates in the treatment group versus four replicates in the control group; spleen and heart: four replicates in the treatment group versus four replicates in the control group for both organs)

2011-04-26 | E-GEOD-28824 | biostudies-arrayexpress

Microarray analysis on livers, spleens and hearts of mice fed an atherogenic diet and supplemented with either oil palm phenolics (OPP) or distilled water

Project description:OPP (1500 ppm gallic acid equivalent (GAE)) was supplemented to BALB/c mice given an atherogenic diet for six weeks to observe for possible anti-atherogenic effects. The control group received distilled water instead of OPP. Livers, spleens and hearts were harvested six weeks after the feeding regimen for gene expression studies. Results from the separate microarray data analysis carried out on the different organs show that OPP attenuated the effects of the atherogenic diet in the organs. Total RNA obtained from livers, spleens and hearts of BALB/c mice given OPP (six weeks after administration of an atherogenic diet) were compared to controls given distilled water (liver: three replicates in the treatment group versus four replicates in the control group; spleen and heart: three replicates in the treatment group versus three replicates in the control group for both organs)

2011-07-25 | E-GEOD-30907 | biostudies-arrayexpress

Microarray analysis on spleens and livers of mice inoculated subcutaneously with J558 myeloma cells and supplemented with oil palm phenolics (OPP)

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Microarray analysis on spleens and livers of mice inoculated subcutaneously with J558 myeloma cells and supplemented with oil palm phenolics (OPP)

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2012-03-17 | E-GEOD-36576 | biostudies-arrayexpress

Atherogenic diet supplemented with oil palm phenolics effect on liver, spleen, and heart

Project description:This SuperSeries is composed of the following subset Series: GSE30905: Microarray analysis on livers, spleens and hearts of mice given distilled water fed with either a normal diet or an atherogenic diet GSE30907: Microarray analysis on livers, spleens and hearts of mice fed an atherogenic diet and supplemented with either oil palm phenolics (OPP) or distilled water Refer to individual Series

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Project description:PFJ (4 ml for a final concentration of 19,000 mg gallic acid equivalent (GAE) per kg diet or 0.86 mg GAE per kcal diet) was supplemented to larvae of fruit flies (Drosophila melanogaster) given a semi-purified diet to observe for possible effects on energy metabolism and lifespan. Larvae were used five days since the egg stage for gene expression studies. Results from the microarray data analysis carried out show that fruit fly larvae given PFJ had up-regulated transport and metabolic processes, while development and morphogenesis processes were down-regulated.

2017-01-06 | GSE93220 | GEO

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