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The cistrome of NKX3.1 in LNCaP prostate cancer cells

ABSTRACT: Here we report the genome-wide set of factors bound by NKX3.1 or control IgG in human prostate cancer cells (LNCaP).

ORGANISM(S): Homo sapiens

PROVIDER: GSE40269 | GEO | 2013/08/21

SECONDARY ACCESSION(S): PRJNA173399

REPOSITORIES: GEO

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The cistrome of NKX3.1 in LNCaP prostate cancer cells

Project description:Here we report the genome-wide set of factors bound by NKX3.1 or control IgG in human prostate cancer cells (LNCaP). Examination of NKX3.1 binding in LNCaP prostate cancer cells

2013-08-21 | E-GEOD-40269 | biostudies-arrayexpress

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Project description:The NKX3.1 homeobox gene functions in mitochondria to regulate oxidative stress To investigate the role of NKX3.1 in regulation of oxidative stress, we employed transcriptome analysis of mouse prostate ( from 4 month old Nkx3.1+/+ and Nkx3.1-/- mice treated with paraquat), and human prostate cells ( RWPE1 cells engineered with empty vector (altered pTRIPZ), NKX3.1 wild type over-expression, and NKX3.1 (R52C) over-expression treated with paraquat). Mouse tissue or human cells were snap frozen for subsequent molecular analysis.

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2016-06-24 | GSE81440 | GEO

Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation

2016-06-24 | E-GEOD-81440 | biostudies-arrayexpress

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Project description:Analysis of transcriptome of prostate tissue from 4-month-old Nkx3.1 +/+ and Nkx3.1 -/- mice. Total RNA obtained from prostate tissues from 4-month-old Nkx3.1 +/+ and Nkx3.1 -/- mice. Prostate tissues were harvested and processed for RNA isolation and transcriptome analysis using the MagMAX RNA isolation kit (Ambion).

2016-06-24 | E-GEOD-81424 | biostudies-arrayexpress

Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Mouse_4M-Prostate_RNA-Seq)

Project description:Analysis of transcriptome of prostate tissue from 4-month-old Nkx3.1 +/+ and Nkx3.1 -/- mice.

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