Methylation profiling

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Genome-wide and single-base resolution DNA methylomes of the Pacific oyster Crassostrea gigas provide insight into the evolution of invertebrate CpG methylation


ABSTRACT: Comparative analysis of the oyster DNA methylomes and that of other animal species revealed that the characteristics of DNA methylation were generally conserved during invertebrate evolution, while some unique features were derived in the insect lineage. The preference of methylation modification on genes originating in the eukaryotic ancestor rather than the oldest genes is unexpected, probably implying that the emergence of methylation regulation in these 'relatively young' genes was critical for the origin and radiation of eukaryotes.

ORGANISM(S): Magallana gigas

PROVIDER: GSE40302 | GEO | 2014/12/18

SECONDARY ACCESSION(S): PRJNA173440

REPOSITORIES: GEO

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