Transcriptomics

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Transcriptome analysis in primary fibroblasts from HOIL-1-deficient patients upon TNF-α or IL-1β stimulation


ABSTRACT: HOIL-1 deficient disease is a new early onset fatal autosomal recessive human disorder charaterized by chronic auto-inflammation, recurrent invasive bacterial infections and progressive muscular amylopectinosis. We studied the effect of TNF-α and IL-1β on transcriptional changes of primary fibroblasts from HOIL-1-, MYD88- and NEMO-deficient patients.

ORGANISM(S): Homo sapiens

PROVIDER: GSE40560 | GEO | 2012/10/28

SECONDARY ACCESSION(S): PRJNA174575

REPOSITORIES: GEO

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