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Transient low-dose decitabine treatment of primary AML samples

ABSTRACT: Genome-wide DNA methylation profiling of primary AML samples treated with 100nM decitabine (DAC), cytarabine (AraC), or DMSO. Eight distinct AML samples were grown using an in vitro stromal co-culture system for 4 days and then treated with either DAC, Ara-C or DMSO for 3 days. DNA was prepared for genome-wide methylation analysis with the Illumina Infinium 450k Human DNA methylation BeadChip. DNA from each sample/treatment was analyzed on duplicate arrays.

ORGANISM(S): Homo sapiens

PROVIDER: GSE40870 | GEO | 2012/12/18

SECONDARY ACCESSION(S): PRJNA175142

REPOSITORIES: GEO

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Transient low-dose decitabine treatment of primary AML samples

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