Transcriptomics

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Expression Analysis of WR99210-treated Mycobacterium tuberculosis H37Rv


ABSTRACT: Investigation of whole genome gene expression level changes in Mycobacterium tuberculosis treated with the DHFR inhibitor WR99210, compared to untreated cells. The antimycobacterial properties of WR99210 are further described in Gerum, A., Ulmer, J., Jacobus, D., Jensen, N., Sherman, D., and C. Sibley. 2002. Novel Saccharomyces cerevisiae screen identifies WR99210 analogues that inhibit Mycobacterium tuberculosis dihydrofolate reductase. Antimicrob Agents Chemother 46(11):3362-3369 [PMID:12384337]

ORGANISM(S): Mycobacterium tuberculosis H37Rv

PROVIDER: GSE40917 | GEO | 2012/09/18

SECONDARY ACCESSION(S): PRJNA175346

REPOSITORIES: GEO

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