Notch Pathway Activation Targets AML Cell Homeostasis and Differentiation: MLL-AF9 transformed LGMP
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ABSTRACT: To determine role of Notch signaling in AML leukemia initiating cells we used a conditional mouse knock-in model of Notch1-IC to induce Notch1-IC expression in MLL-AF9 transformed LGMP. WT and Notch1-IC+ LGMP were analyzed to determined genes controlled by Notch signaling.
ORGANISM(S): Mus musculus
PROVIDER: GSE42260 | GEO | 2013/01/18
SECONDARY ACCESSION(S): PRJNA179480
REPOSITORIES: GEO
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