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Expression data from P0 forebrain of wild-type and Elavl3/Elavl4 double knockout mice.

ABSTRACT: Neuronal Elavl-like (nElavl) RNA binding proteins have three paralogs (Elavl2, Elavl3 and Elavl4) in the mouse genome. This family of RNABPs have been implicated in a variety of post-transcriptional RNA processing mechanisms, including regulation of mRNA stability, alternative splicing, and translational regulation. In this study, using mouse exon arrays, we identify significant differences (p<0.01) in 119 transcripts between wild-type and Elavl3/Elavl4 double knockout forebrain tissue at postnatal day 0.

ORGANISM(S): Mus musculus

PROVIDER: GSE43287 | GEO | 2013/01/05

SECONDARY ACCESSION(S): PRJNA185279

REPOSITORIES: GEO

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Expression data from P0 forebrain of wild-type and Elavl3/Elavl4 double knockout mice.

Project description:Neuronal Elavl-like (nElavl) RNA binding proteins have three paralogs (Elavl2, Elavl3 and Elavl4) in the mouse genome. This family of RNABPs have been implicated in a variety of post-transcriptional RNA processing mechanisms, including regulation of mRNA stability, alternative splicing, and translational regulation. In this study, using mouse exon arrays, we identify significant differences (p<0.01) in 119 transcripts between wild-type and Elavl3/Elavl4 double knockout forebrain tissue at postnatal day 0. A total of 10 samples were analyzed. These samples consisted of 5 littermate pairs of wild-type and Elavl3/Elavl4 double knockout mice.

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Project description:Expression data from P0 forebrain of wild-type and Elavl3/Elavl4 double knockout mice.

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