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Next generation sequencing in ZS rats

ABSTRACT: Next generation sequencing in a rat model of diabetic nephropathy was employed to study in depth the pathogenic alterations involved in progressive diabetic kidney damage. We employed the obese, diabetic ZS rat, a model that develops renal failure and fibrosis, the hallmarks of human disease. We then used RNA-seq to examine in a comprehensive manner the combined effects of renal cells and infiltrating inflammatory cells acting as a pathophysiological unit.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE44375 | GEO | 2014/02/06

SECONDARY ACCESSION(S): PRJNA219464

REPOSITORIES: GEO

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Next generation sequencing in ZS rats

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