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Effect of gas-substrate limitation on barophilic growth of Methanocaldocccus jannaschii at 500 atm.

ABSTRACT: Barophilic growth of the hyperthermophilic methanarchaeon Methanocaldococcus jannaschii occurred when gas-substrate availability did not limit growth. In contrast, when growth was limited by gas transfer, no enhancement of growth was evident and a stress response was exhibited at both high and low pressure. A pressure-induced transcriptional response was evident, regardless of whether growth was enhanced by pressure. High-pressure adaptation of a barophilic organism can thus occur at the transcriptional level, even though the cells are stressed by low substrate availability and do not exhibit accelerated growth. Keywords: stress response, gas substrate limitation, bioreactor volume, high pressure

ORGANISM(S): Methanocaldococcus jannaschii

PROVIDER: GSE4519 | GEO | 2006/08/01

SECONDARY ACCESSION(S): PRJNA94529

REPOSITORIES: GEO

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