Transcriptomics

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Estrogen inhibits lipid content in liver exclusively from membrane receptor signaling


ABSTRACT: Membrane estrogen receptor (ER) alpha stimulates AMP kinase to suppress SREBP1 processing and lipids in liver Here we present evidence that signaling from membrane-localized ERalpha similarly suppresses a subset of mRNAs in the livers of female WT and membrane only estrogen receptor (MOER) transgenic mice but not in estrogen receptor knock out (ERKO) mice

ORGANISM(S): Mus musculus

PROVIDER: GSE45346 | GEO | 2013/05/14

SECONDARY ACCESSION(S): PRJNA193515

REPOSITORIES: GEO

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