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NLRP7 promotes trophoblast lineage differentiation, YY1 binding and alters CpG methylation

ABSTRACT: Genome wide DNA methylation profiling of hESC in the untransduced, scrambled control and with knockdown of NLRP7 in undifferentiated and BMP4 differentiated states using the Illumina HumanMethylation 450 BeadChip. Several genomic sites exhibit altered methylation upon knocking down NLRP7.

ORGANISM(S): Homo sapiens

PROVIDER: GSE45727 | GEO | 2013/11/04

SECONDARY ACCESSION(S): PRJNA196136

REPOSITORIES: GEO

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NLRP7 promotes trophoblast lineage differentiation, YY1 binding and alters CpG methylation

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NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation.

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