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Genome-scale reconstruction of the sigma factor network in E. coli

ABSTRACT: We report the application of single-molecule-based sequencing technology for high-throughput profiling of transcription start sites for Escherichia coli under different conditions. By obtaining sequence from 5' RACE (rapid amplification of cDNA ends) followed by deep sequencing, we generated genome-wide TSS (transcription start site) maps for E. coli. This TSS-map was integrated with ChIP-chip data generated for 6 sigma factors in E. coli, resulting in reconstruction of sigma factor network in E. coli.

ORGANISM(S): Escherichia coli str. K-12 substr. MG1655

PROVIDER: GSE46737 | GEO | 2014/02/05

SECONDARY ACCESSION(S): PRJNA202224

REPOSITORIES: GEO

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