Expression data from blood and biopsies of BKV viremia and nephropathy transplant patients
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ABSTRACT: We study the global gene expression profiles of BKV viremia and nephropathy patients using microarrays in order to better understand the immunologic response to polyomavirus BK (BKV). BKV has become increasingly prevalent since the introduction of more potent immunosuppressive agents. It has been shown that as many as 30% of renal transplant recipients develop asymptomatic viral shedding in the urine shortly after transplant, 10-20% have viremia, and as many as 1-10% can go on to develop overt nephropathy (BKVN) that might lead to graft loss. To date, the genomics of BKV viremia and BKVN have not been investigated thoroughly by microarray.
ORGANISM(S): Homo sapiens
PROVIDER: GSE47199 | GEO | 2013/05/23
SECONDARY ACCESSION(S): PRJNA205070
REPOSITORIES: GEO
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