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Transcriptional Responses in Livers of Adult and Newborn Mice to Aflatoxin B1

ABSTRACT: Susceptibility to the hepatocarcinogen Aflatoxin B1 (AFB1) varies among species and with age. Mice are refractory to carcinogenic and toxic effects of AFB1; however, B6C3F1 mice show transient sensitivity if dosed shortly after birth. We compared age-related differences in gene expression and transcriptional responses to AFB1 in livers of newborn (4-day-old) and adult mice. Keywords: Transcriptional response to a carcinogen

ORGANISM(S): Mus musculus

PROVIDER: GSE4740 | GEO | 2009/01/01

SECONDARY ACCESSION(S): PRJNA95681

REPOSITORIES: GEO

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Transcription profiling of mouse livers of adult and newborn animal response to Aflatoxin B1

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