Regulation of Mouse Lens Development and Gene Expression by Krüppel-Like Factor 4
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ABSTRACT: Conditional disruption of Klf4 in the ectoderm-derived tissues of the eye results in defective cornea, conjunctiva and the lens. Expression of Klf4 is first detected in the embryonic day-12 (E12) mouse lens, peaks at E16, and declines thereafter. Lenses from Mice which were conditional null for Klf4 (Klf4CN) were characterized by morphology and transcriptome.
ORGANISM(S): Mus musculus
PROVIDER: GSE47694 | GEO | 2013/07/01
SECONDARY ACCESSION(S): PRJNA207302
REPOSITORIES: GEO
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