Transcriptomics

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Expression profiles of wildtype and SHOX transgenic embryonic mouse limbs


ABSTRACT: Deficiency of the human short stature homeobox-containing gene (SHOX) has been identified in several disorders characterized by reduced height and skeletal anomalies such as Turner, Leri-Weill and Langer syndrome as well as idiopathic short stature. Although highly conserved in vertebrates, rodents lack a SHOX orthologue. Here, we compared gene expression profiles of wildtype and SHOX transgenic mouse limbs using microarray experiments to identify SHOX target genes in the developing limb.

ORGANISM(S): Mus musculus

PROVIDER: GSE47902 | GEO | 2014/08/13

SECONDARY ACCESSION(S): PRJNA208290

REPOSITORIES: GEO

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