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Expression data from growth restricted fetal rat pancreatic islets

ABSTRACT: Intrauterine growth restriction is a common complication of pregnancy. We induce IUGR in rats by bilateral uterine artery ligation at e18 of a 23 day gestation. This mimics placental insufficiency. This array experiment compares gene expression changes in isolated pancreatic islets from e19, 24 hours post-surgery , or sham operated animals.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE48655 | GEO | 2013/07/10

SECONDARY ACCESSION(S): PRJNA210938

REPOSITORIES: GEO

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Expression data from growth restricted fetal rat pancreatic islets

Project description:Intrauterine growth restriction is a common complication of pregnancy. We induce IUGR in rats by bilateral uterine artery ligation at e18 of a 23 day gestation. This mimics placental insufficiency. This array experiment compares gene expression changes in isolated pancreatic islets from e19, 24 hours post-surgery , or sham operated animals. RNA from isolated pancreatic islets from e19 fetuses, pooled from an entire litter. There are 4 control (sham) operated litters and 4 IUGR litters.

2013-07-10 | E-GEOD-48655 | biostudies-arrayexpress

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