Genomics

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Genome-wide mapping of SPDEF and ESR1 binding in MCF-7 cells (ChIP-seq)


ABSTRACT: Using a transcriptional network derived from 2000 breast cancer gene expression profiles we identify the master regulators (MRs) of FGFR2 signalling. To validate the identified regulons, we examined whether there was enrichment of TF binding near the transcription start sites (TSS) of genes found in the regulons of a particular MR.

ORGANISM(S): Homo sapiens

PROVIDER: GSE48930 | GEO | 2013/07/17

SECONDARY ACCESSION(S): PRJNA212328

REPOSITORIES: GEO

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