MiRNA profile induced by RET/PTC1 oncogene in human thyrocytes

ABSTRACT: To obtain a PTC cell model, primary human thyrocytes have been infected with a retrovirus expressing RET/PTC1 oncogene, using parental thyrocytes as control. The obtained RET/PTC-dependent differential miRNA expression profile, representing the effects of RET/PTC1 oncogene present in about one third of papillary thyroid carcinoma (PTC), models the early event of thyrocytes transformation ending to PTC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE49400 | GEO | 2014/06/30

SECONDARY ACCESSION(S): PRJNA213877

REPOSITORIES: GEO