Effects of Treg depletion in dystrophic muscle.
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ABSTRACT: CD4+Foxp3+ regulatory T cells (Tregs) accumulate in skeletal muscle from dystrophin-deficient mdx mice. Analysis of global gene expression in muscles from mdx mice treated with anti-CD25 compared with muscles from mdx mice treated with control antibody revealed that Tregs partially protect mdx mice from muscle pathology and promote muscle repair/regeneration.
ORGANISM(S): Mus musculus
PROVIDER: GSE50095 | GEO | 2013/12/15
SECONDARY ACCESSION(S): PRJNA216019
REPOSITORIES: GEO
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