Genomics

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Genome-wide maps of H3K27ac, PPARβ/δ and Pol II localization in HUVECs


ABSTRACT: H3K27Ac is one of the expressed enhancer markers, PPARβ/δ is a transcription factor and Pol II (RNA polymerase II) is an enzyme which catalyzes the transcription of DNA to synthesize precursors of mRNA and most snRNA and microRNA. These genomic localization in endothelial cells is unknown in endothelial cells. This time, we established a new antibody for H3K27ac, PPARβ/δ and Pol II and performed ChIP-seq to identify H3K27ac, PPARβ/δ and Pol II binding site in whole genome manner under PPARβ/δ agonist and/or hypoxia.

ORGANISM(S): Homo sapiens

PROVIDER: GSE50144 | GEO | 2014/03/06

SECONDARY ACCESSION(S): PRJNA216152

REPOSITORIES: GEO

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