Transcriptomics

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Differential analysis of neural crest and mesodermally derived VSMC in the aorta


ABSTRACT: Vascular smooth muscle cells (VSMCs) are derived from distinct embryonic origins. Vessels originating from differing smooth muscle cell populations have distinct vascular and pathological properties of calcification, atherosclerosis, and structural defects such as aneurysm and coarctation. We hypothesized that domains within a vessel vary in phenotype based on embryonic origin. We used microarrays to detail the expression differences in vasculature of different embryonic origin.

ORGANISM(S): Mus musculus

PROVIDER: GSE50251 | GEO | 2014/08/26

SECONDARY ACCESSION(S): PRJNA217337

REPOSITORIES: GEO

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