Loss of beta-catenin triggers oxidative stress and impairs hematopoietic regeneration
Ontology highlight
ABSTRACT: Accidental or deliberate ionizing radiation exposure is fatal due to widespread hematopoietic destruction. However, little is known about either the course of injury or the definitive molecular pathways that regulate the subsequent regenerative response. We have investigated the spatial and temporal consequences of radiation injury on the hematopoietic system and show the Wnt signaling pathway is critially important for regeneration.
ORGANISM(S): Mus musculus
PROVIDER: GSE50620 | GEO | 2016/08/31
SECONDARY ACCESSION(S): PRJNA218099
REPOSITORIES: GEO
ACCESS DATA