Transcriptomics

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Global reprogramming of the cellular translational landscape facilitates cytomegalovirus replication


ABSTRACT: Genome-wide profiling establishes that human cytomegalovirus (HCMV) exerts an extensive, unforeseen level of specific control over which cellular mRNAs are recruited to or excluded from polyribosomes. The landscape of translationally-regulated host mRNAs regulates HCMV replication. The HCMV imposed translational signature shares similarities with cancer cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE50938 | GEO | 2013/11/01

SECONDARY ACCESSION(S): PRJNA219395

REPOSITORIES: GEO

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