Using a rhabdomyosarcoma patient-derived xenograft to examine precision medicine approaches and model acquired resistance
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ABSTRACT: Original patient tumor is directly implanted in mice xenografts. Tumor is propagated to multiple mice for conduct of 6 arm treatment trials and control. Therapies are selected based on T0 and F0 genomic profiles. ICE-T refractory tumor are implanted and additional 6 arm treatment trial and control conducted based on genomic profiles of F2 generation mice to suggested therapies
ORGANISM(S): Homo sapiens
PROVIDER: GSE51130 | GEO | 2014/07/22
SECONDARY ACCESSION(S): PRJNA221341
REPOSITORIES: GEO
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