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Long-term androgen withdrawal and treatment (R1881) of LNCaP-FGC prostate cancer cells

ABSTRACT: LNCaP cells were cultures in steroid depleted medium for 5 days before treatment with synthetic androgen (R1881, 10nM) for 16h. Transcriptomics analysis was performed to compare gene expression changes induced by androgen withdrawal or androgen treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE51460 | GEO | 2013/10/22

SECONDARY ACCESSION(S): PRJNA223242

REPOSITORIES: GEO

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Long-term androgen withdrawal and treatment (R1881) of LNCaP-FGC prostate cancer cells

Project description:LNCaP cells were cultures in steroid depleted medium for 5 days before treatment with synthetic androgen (R1881, 10nM) for 16h. Transcriptomics analysis was performed to compare gene expression changes induced by androgen withdrawal or androgen treatment. Genome-wide transcriptomic analysis of LNCaP cells grown in steroid depleted medium, normal (steroid-containing) medium and R1881 treated cells was performed using the Agilent platform

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