Transcriptomics

Dataset Information

0

MRNA profile of CD8 T cells from chronic HBV patients


ABSTRACT: The low frequency of HBV-specific CD8+ T cells in the peripheral blood of CHB patients has limited studies of the mechanisms underlying HBV-induced T cell exhaustion. Similar to the expansion defect displayed in HBV-specific CD8+ T cells, TCR-induced proliferation of global CD8+ T cells is impaired in a fraction of chronic HBV (CHB) patients. Thus, examining the molecular regulation of global CD8+ T cell function in CHB patients may provide insight into the exhaustion of HBV-specific CD8+ T cells. We used microarrays to detail the global programme of gene expression of CD8 T cells from CHB patients who have not received anti-viral treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE51489 | GEO | 2016/07/01

SECONDARY ACCESSION(S): PRJNA223293

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2016-07-01 | E-GEOD-51489 | biostudies-arrayexpress
2023-05-24 | GSE217838 | GEO
2023-02-03 | GSE224283 | GEO
2024-07-01 | GSE259231 | GEO
2018-08-17 | PXD007896 | Pride
2015-04-15 | E-GEOD-67882 | biostudies-arrayexpress
2022-07-27 | GSE202557 | GEO
2016-08-21 | E-GEOD-84044 | biostudies-arrayexpress
2017-01-11 | GSE67801 | GEO
2020-08-18 | GSE156347 | GEO