Transcriptomics

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Pre-Collaborative Cross lung gene expression after allergen challenge


ABSTRACT: The Collaborative Cross (CC) recombinant inbred panel was conceived as an ideal resource for mammalian system genetics. The pre-CC is a proof-of-concept experiment involving CC lines that have undergone at least five generations of inbreeding. Siblings from these lines were each involved in one of four distinct phenotyping arms, then genotyped on a high-density Affymetrix platform. These mice were initially described in the following reference. Genome Research 2011 Aug;21(8):1213-22 (PMID: 21406540). The goal of this specific project was to identify gene expression QTL using lung tissue from pre-CC mice that were sensitized and challenged with house dust mite allergen (namely, Der p 1).

ORGANISM(S): Mus musculus

PROVIDER: GSE51768 | GEO | 2013/11/15

SECONDARY ACCESSION(S): PRJNA225021

REPOSITORIES: GEO

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