MiRNA expression signatures in Tif1b-deficient hematopoietic stem cell
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
PROVIDER: GSE52282 | GEO | 2013/11/12
SECONDARY ACCESSION(S): PRJNA227338
REPOSITORIES: GEO
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Project description:miRNA expression analyses of Tif1b-deficient hematopoietic stem cells (HSCs). Tif1b loss leds to rapid depletion of HSCs. Expression analyses provide insight into the role of Tif1b in the maitenance of HSC. HSCs (c-Kit+ Sca1+ Lineage- ) are sorted from adult bone marrow and are subjected into microarray analyses.
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Project description:Gene expression analyses of Tif1b-deficient hematopoietic stem cells (HSCs). Tif1b loss leads to rapid depletion of HSCs. Expression analyses provide insight into the role of Tif1b in the maitenance of HSC. HSCs (c-Kit+ Sca1+ Lineage- ) are sorted from fetal liver or adult bone marrow and are subjected into microarray analyses.
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