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An Immunosignature system for diagnosis of cancer [Cancer immunosignaturing - test 2]

ABSTRACT: This dataset contains peptide array information from 1516 patients from 12 different cancer types, 2 infectious diseases, and healthy controls using leave one out cross validation. This array is library 2 (GPL14921).

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE52581 | GEO | 2013/12/15

SECONDARY ACCESSION(S): PRJNA229413

REPOSITORIES: GEO

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An Immunosignature system for diagnosis of cancer [Cancer immunosignaturing - test 2]

Project description:This dataset contains peptide array information from 1516 patients from 12 different cancer types, 2 infectious diseases, and healthy controls using leave one out cross validation. This array is library 2 (GPL14921). A 1:500 dilution of human serum is added to a peptide array (GPL14921). This array is a one-up design, with 10286 peptides printed in duplicate on a standard glass microscope slide. 1516 patients samples from 14 different diseases and 1 control cohort were analyzed

2013-12-15 | E-GEOD-52581 | biostudies-arrayexpress

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An Immunosignature system for diagnosis of cancer

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Identification of Vaccinia Virus HLA Class I Peptides Presented by the Immune System

Project description:Seeking to identify HLA class I peptides that originate from vaccinia virus proteins to understand the mechanism of immune protection. Note that vaccinia-infected B cells will still continue to present (primarily) a wide variety of peptides originating from endogenous proteins; this data set contains evidence for more than 5000 such peptides. The objective and challenge is to detect and identify the peptides that originate from the pathogen (vaccinia virus) in the presence (background) of this large number of endogensous 'self' peptides. Keywords: Peptide search results from multiple injections of multiple strong cation exchange fractions combined into one set of results.

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