Transcriptomics

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Cardiac gene expression after transgenic overexpression or deletion of MeCP2 in cardiomyocytes


ABSTRACT: To identify potentially regulated target genes of MeCP2 we used celltype-specific models for transgenic overexpression and ablation of MeCP2. Gene expression was analyzed in cardiac biopsies of adult male mice. The study contains three different treatment groups: 1. healthy mice (Sham), 2. mice suffering from 4-6 weeks of cardiac pressure overload (TAC) and 3. with a reversible induction of TAC (TAC followed by 2 weeks without TAC)

ORGANISM(S): Mus musculus

PROVIDER: GSE52796 | GEO | 2015/12/22

SECONDARY ACCESSION(S): PRJNA230054

REPOSITORIES: GEO

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