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MiRNA expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study2]

ABSTRACT: Using a PTSD mouse model, we investigated the longitudinal transcriptomic changes in heart tissues after the exposure to stress through intimidation

ORGANISM(S): Merkel cell polyomavirus Mus musculus Rattus norvegicus Human gammaherpesvirus 8 JC polyomavirus Betapolyomavirus macacae Homo sapiens Human immunodeficiency virus 1 Human betaherpesvirus 5 Human alphaherpesvirus 2 Betapolyomavirus hominis Human alphaherpesvirus 1 Murid gammaherpesvirus 4 human gammaherpesvirus 4 Mus musculus cytomegalovirus 2 Murid betaherpesvirus 1

PROVIDER: GSE52872 | GEO | 2013/12/04

SECONDARY ACCESSION(S): PRJNA230438

REPOSITORIES: GEO

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miRNA expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study1]

Project description:Using a PTSD mouse model, we investigated the longitudinal transcriptomic changes in heart tissues after the exposure to stress through intimidation

2013-12-04 | GSE52869 | GEO

Gene expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study1]

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Gene expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study2]

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miRNA expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study1]

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Gene expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study2]

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miRNA expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study2]

Project description:Using a PTSD mouse model, we investigated the longitudinal transcriptomic changes in heart tissues after the exposure to stress through intimidation We designed our time-course study (Study II) with three experimental conditions where we varied the length of time that subservient mice were exposed to aggressor mice with the same length of rest time after the exposure (1day). The conditions included were 1day-exposure (T1R1), 2day-exposure (T2R1) and 3day-exposure (T3R1). We designed our initial study (Study I) with four experimental conditions where we varied the length of time that subservient mice were exposed to aggressor mice and the length of rest time after the exposure. The conditions included were short exposure-short rest (T5R1-T indicates the number of days of trauma exposure; R indicates the number of days of rest after exposure), short exposure-long rest (T5R10), long exposure-short rest (T10R1) and long exposure-long rest (T10R42)

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Gene expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD) [Study1]

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Expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD)

Project description:This SuperSeries is composed of the SubSeries listed below.

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Expression signatures in heart tissues of mice simulating posttraumatic stress disorder (PTSD)

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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Project description:To investigate gene expression signatures in PTSD, we used microarray and performed blood-based transcriptome profiling. Our analyses identified key genes and molecular pathways that can be centrally involved in the etiology of PTSD.

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