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Expression data from control and Snai1 knockout embryonic stem cells (ESCs)

ABSTRACT: Snail1 is a master epithelial-mesenchymal trisition (EMT) factor but its role in ESC maintenance is unknown. We used microarrays to compare the global gene expression between control and Snai1 knockout ESCs.

ORGANISM(S): Mus musculus

PROVIDER: GSE53107 | GEO | 2013/12/10

SECONDARY ACCESSION(S): PRJNA231001

REPOSITORIES: GEO

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Expression data from control and Snai1 knockout embryonic stem cells (ESCs)

Project description:Snail1 is a master epithelial-mesenchymal trisition (EMT) factor but its role in ESC maintenance is unknown. We used microarrays to compare the global gene expression between control and Snai1 knockout ESCs. RNA extracted from control and Snai1 knockout ESCs were hybridizated on Affymetrix microarrays.

2013-12-10 | E-GEOD-53107 | biostudies-arrayexpress

Expression data from control (F/F) and Snai1 knockout (KO) embryoid body (EB) and teratoma ™

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Expression data from control (F/F) and Snai1 knockout (KO) embryoid body (EB) and teratoma ™

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Expression data of control (F/F) and Snai1 knockout (KO) Flk1+/- cells

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Project description:Snail1 is a master factor of epithelial to mesenchymal transitioin (EMT), however, its role in embryonic vascular development is largely undefined. We used microarrays to compare the global programme of gene expression between cultured WT and Snai1 KO embyronic ECs. ECs isolated from E10.5 Snail1f/f embryos were infected with adeno-?Gal or -Cre to generate WT and Snail1 KO ECs. RNA were collected for Affymetrix microarrays.

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Retinoic acid induces Snai1 in stem cells of the preimplantation blastocyst to initiate differentiation

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