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An analysis of genomic structural alteration in three human ES cell lines.

ABSTRACT: To elucidate frequencies of genomic structural alterations, we performed an analysis using a SNP genotyping array (Illumina HumanCytoSNP-12 v2.1 DNA Analysis BeadChip Kit) for three human ES cell lines, namely, SEES-1, SEES-2, and SEES-3. Samples were collected after 4 to 60 passages to detect structural mutations occurred during the cell cultivation processes. Our results suggested a higher genomic stability of the ES cells compared to some well-known normal cell lines.

ORGANISM(S): Homo sapiens

PROVIDER: GSE54576 | GEO | 2015/05/20

SECONDARY ACCESSION(S): PRJNA237441

REPOSITORIES: GEO

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An analysis of genomic structural alteration in three human ES cell lines.

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