Transcriptomics

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Indole-3-Carbinol Preferentially Target ERα-Positive Breast Cancer Cells.


ABSTRACT: Indole-3-carbinol (I3C) is a natural anti-carcinogenic compound found at high concentrations in Brassica vegetables. ER-positive cell lines demonstrated the greatest sensitivity to the anti-tumor effects of I3C compared to ER-negative breast cancer cell lines. Gene expression analysis was performed to identify genes and pathways that accounted for sensitivity to I3C. Microarray analysis performed using Illumina HT-12 v4 expression arrays

ORGANISM(S): Homo sapiens

PROVIDER: GSE55897 | GEO | 2014/08/12

SECONDARY ACCESSION(S): PRJNA241265

REPOSITORIES: GEO

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